Dr. Pratima   Gupta

Department Bio Technology
Designation Professor
Educational Qualification Ph.D. in Microbiology
E-Mail pgupta.bt@nitrr.ac.in
Contact Number 9229557174
Areas of Interest

Bioprospects of microorganisms: Microbial biofilms, Microbial products and process technology. Microbial electrochemical technology for biotechnological applications, BioMicrofluidics.

Publications

PATENTS

  1. Title of Invention: Microfluidic Lab-On-Chip Device for Biofilm Growth Measurement and Method of Fabricating the Same; Type of Invention: Product & Process; Patent Office: Intellectual Property India Patent No. - 569700.
  2. Title of Invention: Microbial electrochemical system for generation of Hydrogen peroxide and in-situ valorization of agricultural waste; Type of Invention: Product & Process; Patent Office: Intellectual Property India; Publication Date: 22/12/2023.
  3. Title of Invention: An In-Vitro Biofilm System for Growth and Real-Time Analysis of Microbial Biofilm; Type of Invention: Product & Process; Patent Office: Intellectual Property IndiaPatent No. - 538157.
  4. Title of Invention: Biofilm Infection Simulator System; Type of Invention: Design; Patent Office: Intellectual Property India; Design No. - 373428-001. 
  5. Title of Invention: Real-Time Microchannel Optopotentiometric Biofilm System; Type of Invention: Design; Patent Office: Intellectual Property India; Design No. - 376815-001. 
  6. Title of Invention: Real-Time Microchannel Potentiometric Biofilm System; Type of Invention: Design; Patent Office: Intellectual Property India; Design No. - 384592-001. 
RESEARCH SUPERVISION

Ph.D.:

07 (Completed)
  1. Piyush Parkhey
  2. Suresh Chand Phulara
  3. Kush Nayak
  4. Batul Diwan
  5. Preeti Chaturvedi
   6. Dhruva Mukhopadhyay
  7. Anuj Rohatgi
  
04 (Ongoing)
   1. Anmol Kulshrestha
   2. Changsomba Chang
   3. Aman Singh
   4. Laxmi Narayan Tiwari 
 
PUBLICATIONS
  1. Chandrawanshi, S., Chang, C. and Gupta, P. (2026), Biomass to bioflavor: microbial electrochemical-assisted depolymerization of lignin and recovery of vanillin. Biofuels, Bioprod. Bioref.. https://doi.org/10.1002/bbb.70077.
  2. Anmol Kulshrestha, Pratima Gupta, Multi-computational screening identifies homovanillic acid as a potential SAP5 inhibitor against Candida albicans biofilms, Computational Biology and Chemistry, Volume 118, 2025, 108453, ISSN 1476-9271, https://doi.org/10.1016/j.compbiolchem.2025.108453.
  3. Kulshrestha, A., & Gupta, P. (2025). Control of Candida albicans and Staphylococcus aureus dual species interkingdom biofilm development via SAP5 inhibition. Future Microbiology20(12), 779–791. https://doi.org/10.1080/17460913.2025.2539011.
  4. Kulshrestha, A., Gupta, P., Singh, V.K. et al. Real-time monitoring of Candida albicans biofilm growth and 4-HPA-mediated inhibition using an optoelectrochemical platform. Microfluid Nanofluid 29, 38 (2025). https://doi.org/10.1007/s10404-025-02810-x.
  5. Kulshrestha, A., Gupta, P. & Negi, S.S. Sustainable and optimized fabrication of microfluidic devices for electrochemical detection and monitoring of microbial biofilms. Microfluid Nanofluid 29, 34 (2025). https://doi.org/10.1007/s10404-025-02804-9.
  6. Anuj Rohatgi, Pratima Gupta, Antibiofilm action of phytochemicals on Enterobacteriaceae, Journal of Bioscience and Bioengineering, Volume 139, Issue 5, 2025, Pages 362-368, ISSN 1389-1723, https://doi.org/10.1016/j.jbiosc.2025.01.007.
  7. Chandrawanshi, S., Chang, C. & Gupta, P. Microbial electrochemical in situ conversion of kraft lignin into ferulic acid and its recovery. Biomass Conv. Bioref. 15, 18345–18359 (2025). https://doi.org/10.1007/s13399-025-06654-x.
  8. Anuj Rohatgi, Pratima Gupta, Benzoic acid derivatives as potent antibiofilm agents against Klebsiella pneumoniae biofilm, Journal of Bioscience and Bioengineering, Volume 136, Issue 3, 2023, Pages 190-197, ISSN 1389-1723, https://doi.org/10.1016/j.jbiosc.2023.06.011.
  9. Kulshrestha, A., & Gupta, P. (2024). Real-time biofilm detection techniques: advances and applications. Future Microbiology, 19(11), 1003–1016. https://doi.org/10.1080/17460913.2024.2350285.
  10. Changsomba Chang, Pratima Gupta, Catalytic valorization of Kraft lignin into feedstock chemicals with methyltrioxorhenium (MTO) catalyst in microbial electrochemical cell, International Journal of Biological Macromolecules, Volume 254, Part 2, 2024,127631, ISSN 0141-8130, https://doi.org/10.1016/j.ijbiomac.2023.127631.
  11. Kulshrestha, A., Gupta, P. Combating polymicrobial biofilm: recent approaches. Folia Microbiol 68, 495–505 (2023). https://doi.org/10.1007/s12223-023-01070-y.
  12. Kulshrestha, A., & Gupta, P. (2023). Secreted Aspartyl Proteases Family: A Perspective Review on the Regulation Of Fungal Pathogenesis. Future Microbiology, 18(5), 295–309. https://doi.org/10.2217/fmb-2022-0143.
  13. Chang, C. and Gupta, P. (2023), Valorization of lignin to obtain platform chemicals via bio-electrochemical systems: batch and fed-batch mode analysis. J Chem Technol Biotechnol, 98: 1312-1320. https://doi.org/10.1002/jctb.7349.
  14. Changsomba Chang and Pratima Gupta, Biomacromolecules 2023 24 (3), 1220-1232, DOI: 10.1021/acs.biomac.2c01281.
  15. Dhruva Mukhopadhyay, Changsomba Chang, Mohit Kulsreshtha, Pratima Gupta. (2023). Bio-separation of value-added products from Kraft lignin: A promising two-stage lignin biorefinery via microbial electrochemical technology. International Journal of Biological Macromolecules. doi.org/10.1016/j.ijbiomac.2022.12.055.
  16. Aadil, K.R., Nathani, A., Rajendran, A. et al. Investigation of human hair keratin-based nanofibrous scaffold for skin tissue engineering application. Drug Deliv. and Transl. Res. 14, 236–246 (2024). https://doi.org/10.1007/s13346-023-01396-7.
  17. Panwar, D. S., & Gupta, P. (2025). Comparative analysis of microwaved-assisted blue and green-emitting carbon quantum dots for enhanced bacterial bioimaging. Indian Chemical Engineer, 1–11. https://doi.org/10.1080/00194506.2025.2516559.Changsomba Chang, Pratima Gupta, In-situ degradation of Amphotericin B in a microbial electrochemical cell containing wastewater, Chemosphere, Volume 309, Part 2, 2022, 136726, ISSN 0045-6535, https://doi.org/10.1016/j.chemosphere.2022.136726.
  18. Dhruva Mukhopadhyay, Nawaz Khan, Neha Kamal, Sunita Varjani, Shivani Singh, Raveendran Sindhu, Pratima Gupta, Preeti Chaturvedi Bhargava, Degradation of β-lactam antibiotic ampicillin using sustainable microbial peroxide producing cell system, Bioresource Technology, Volume 361, 2022, 127605, ISSN 0960-8524, https://doi.org/10.1016/j.biortech.2022.127605.
  19. C. Chang, P. Gupta, Fuel Cells 2022, Economical and sustainable microbial peroxide-producing cell utilizing domestic sewage water and its contemporaneous treatment 22, 186. https://doi.org/10.1002/fuce.202200086.
  20. Batul Diwan, Pratima Gupta, Key media microsupplements for boosting de novo lipogenesis in an oleaginic yeast isolate, Journal of Bioscience and Bioengineering, Volume 134, Issue 2, 2022, Pages 95-104, ISSN 1389-1723, https://doi.org/10.1016/j.jbiosc.2022.03.008.
  21. Anmol Kulshrestha, Pratima Gupta, Polymicrobial interaction in biofilm: mechanistic insights, Pathogens and Disease, Volume 80, Issue 1, 2022, ftac010, https://doi.org/10.1093/femspd/ftac010.
  22. Dhruva Mukhopadhyay, Pratima Gupta, Ritesh Patidar, Vimal Chandra Srivastava, Microbial peroxide producing cell mediated lignin valorization, International Journal of Biological Macromolecules, Volume 202, 2022, Pages 431-437, ISSN 0141-8130, https://doi.org/10.1016/j.ijbiomac.2021.12.126.
  23. Anuj Rohatgi, Pratima Gupta, Natural and synthetic plant compounds as anti-biofilm agents against Escherichia coli O157:H7 biofilm, Infection, Genetics and Evolution, Volume 95, 2021, 105055, ISSN 1567-1348, https://doi.org/10.1016/j.meegid.2021.105055.
  24. Phulara, S.C., Pandey, S., Jha, A. et al. Hemiterpene compound, 3,3-dimethylallyl alcohol promotes longevity and neuroprotection in Caenorhabditis elegans. GeroScience 43, 791–807 (2021). https://doi.org/10.1007/s11357-020-00241-w.
  25. Preeti Chaturvedi, Parul Shukla, Balendu Shekher Giri, Pankaj Chowdhary, Ram Chandra, Pratima Gupta, Ashok Pandey, Prevalence and hazardous impact of pharmaceutical and personal care products and antibiotics in environment: A review on emerging contaminants, Environmental Research, Volume 194, 2021, 110664, ISSN 0013-9351, https://doi.org/10.1016/j.envres.2020.110664.
  26. Preeti Chaturvedi, Balendu Shekher Giri, Parul Shukla, Pratima Gupta, Recent advancement in remediation of synthetic organic antibiotics from environmental matrices: Challenges and perspective, Bioresource Technology, Volume 319, 2021, 124161, ISSN 0960-8524, https://doi.org/10.1016/j.biortech.2020.124161.
  27. Preeti Chaturvedi, Deepshi Chaurasia, Ashok Pandey, Pratima Gupta, Co-occurrence of multidrug resistance, β-lactamase and plasmid mediated AmpC genes in bacteria isolated from river Ganga, northern India, Environmental Pollution, Volume 267, 2020, 115502, ISSN 0269-7491, https://doi.org/10.1016/j.envpol.2020.115502.
  28. Diwan, B., Gupta, P. A Deuteromycete Isolate Geotrichum candidum as Oleaginous Cell Factory for Medium-Chain Fatty Acid-Rich Oils. Curr Microbiol 77, 3738–3749 (2020). https://doi.org/10.1007/s00284-020-02155-4.
  29. Batul Diwan, Pratima Gupta, Synthesis of MCFA and PUFA rich oils by enzymatic structuring of flax oil with single cell oils, LWT, Volume 133, 2020, 109928, ISSN 0023-6438, https://doi.org/10.1016/j.lwt.2020.109928.
  30. Parkhey, P., Ram, A. K., Diwan, B., Eswari, J. S., & Gupta, P. (2020). Artificial neural network and response surface methodology: a comparative analysis for optimizing rice straw pretreatment and saccharification. Preparative Biochemistry & Biotechnology, 50(8), 768–780. https://doi.org/10.1080/10826068.2020.1737816.
  31. Diwan, B., Gupta, P. Conversion of Rice straw to caprylic acid-rich microbial oils by oleaginous yeast isolates. Biomass Conv. Bioref. 12, 5901–5914 (2022). https://doi.org/10.1007/s13399-020-01039-8.
  32. Keshaw R. Aadil, Akash Nathani, Chandra S. Sharma, Nibedita Lenka, Pratima Gupta, Investigation of poly(vinyl) alcohol-gellan gum based nanofiber as scaffolds for tissue engineering applications, Journal of Drug Delivery Science and Technology, Volume 54, 2019, 101276, ISSN 1773-2247, https://doi.org/10.1016/j.jddst.2019.101276.
  33. Pandey, S., Phulara, S. C., Jha, A., Chauhan, P. S., Gupta, P., & Shukla, V. (2019). 3-Methyl-3-buten-1-ol (isoprenol) confers longevity and stress tolerance in Caenorhabditis elegans. International Journal of Food Sciences and Nutrition, 70(5), 595–602. https://doi.org/10.1080/09637486.2018.1554031.
  34. Suresh Chandra Phulara, Preeti Chaturvedi, Deepshi Chaurasia, Batul Diwan, Pratima Gupta, Modulation of culture medium confers high-specificity production of isopentenol in Bacillus subtilis, Journal of Bioscience and Bioengineering, Volume 127, Issue 4, 2019, Pages 458-464, ISSN 1389-1723, https://doi.org/10.1016/j.jbiosc.2018.10.002.
  35. Batul Diwan, Pratima Gupta, Broth recycling in high carbon demanding single cell oil fermentation increased the product to effluent generation ratio, Process Biochemistry, Volume 75, 2018, Pages 68-73, ISSN 1359-5113, https://doi.org/10.1016/j.procbio.2018.09.008.
  36. Suresh Chandra Phulara, Deepshi Chaurasia, Batul Diwan, Preeti Chaturvedi, Pratima Gupta, In-situ isopentenol production from Bacillus subtilis through genetic and culture condition modulation, Process Biochemistry, Volume 72, 2018, Pages 47-54, ISSN 1359-5113, https://doi.org/10.1016/j.procbio.2018.06.019.
  37. Diwan, B., Parkhey, P. & Gupta, P. From agro-industrial wastes to single cell oils: a step towards prospective biorefinery. Folia Microbiol 63, 547–568 (2018). https://doi.org/10.1007/s12223-018-0602-7.
  38. Aadil, K. R., Nathani, A., Sharma, C. S., Lenka, N., & Gupta, P. (2018). Fabrication of biocompatible alginate-poly(vinyl alcohol) nanofibers scaffolds for tissue engineering applications. Materials Technology, 33(8), 507–512. https://doi.org/10.1080/10667857.2018.1473234.
  39. Lei Hu, Jiaxing Xu, Shouyong Zhou, Aiyong He, Xing Tang, Lu Lin, Jiming Xu, and Yijiang Zhao. ACS Catalysis 2018 8 (4), 2959-2980. DOI: 10.1021/acscatal.7b03530.
  40. Kush Kumar Nayak, Pratima Gupta, Study of the keratin-based therapeutic dermal patches for the delivery of bioactive molecules for wound treatment, Materials Science and Engineering: C, Volume 77, 2017, Pages 1088-1097, ISSN 0928-4931, https://doi.org/10.1016/j.msec.2017.04.042.
  41. Pratima Gupta, Batul Diwan, Bacterial Exopolysaccharide mediated heavy metal removal: A Review on biosynthesis, mechanism and remediation strategies, Biotechnology Reports, Volume 13, 2017, Pages 58-71, ISSN 2215-017X, https://doi.org/10.1016/j.btre.2016.12.006.
  42. Piyush Parkhey, Pratima Gupta, Improvisations in structural features of microbial electrolytic cell and process parameters of electrohydrogenesis for efficient biohydrogen production: a review, Renewable and Sustainable Energy Reviews, Volume 69, 2017, Pages 1085-1099, ISSN 1364-0321, https://doi.org/10.1016/j.rser.2016.09.101.
  43. Parkhey, P., Gupta, P., & Eswari, J. S. (2017). Optimization of Cellulase Production from Isolated Cellulolytic Bacterium: Comparison between Genetic Algorithms, Simulated Annealing, and Response Surface Methodology. Chemical Engineering Communications, 204(1), 28–38. https://doi.org/10.1080/00986445.2016.1230736.
  44. Phulara SC, Chaturvedi P, Gupta P2016.Isoprenoid-Based Biofuels: Homologous Expression and Heterologous Expression in Prokaryotes. Appl Environ Microbiol82:.https://doi.org/10.1128/AEM.01192-16.
  45. Pratima Gupta, Kush Kumar Nayak, Optimization of keratin/alginate scaffold using RSM and its characterization for tissue engineering, International Journal of Biological Macromolecules, Volume 85, 2016, Pages 141-149, ISSN 0141-8130, https://doi.org/10.1016/j.ijbiomac.2015.12.010.
  46. Kush Kumar Nayak, Pratima Gupta, In vitro biocompatibility study of keratin/agar scaffold for tissue engineering, International Journal of Biological Macromolecules, Volume 81, 2015, Pages 1-10, ISSN 0141-8130, https://doi.org/10.1016/j.ijbiomac.2015.07.025.

 

 

Other Info.

Sponsored Projects:

Project 1:

Title of the project: In situ application of microbial peroxide producing cell for oxidative depolymerization of lignin and its subsequent valorisation 

Principal Investigator: Dr. Pratima Gupta

Funding Agency: Science and Engineering Research Board (SERB), Dept. of Science & Technology (DST), Govt. of India.

Status: Completed 

Project 2:

Title of the project: Design of a microbial electrolytic cell reactor for economic and energy efficient biohydrogen production from leafy biomass by electrohydrogenesis

Principal Investigator: Dr. Pratima Gupta

Funding Agency: Ministry of New and Renewable Energy (MNRE), Govt. of India

Status: Completed 

Project 3:

Title of the project: Enzymatic hydrolysis of rice husk straw and its conversion into biohydrogen by dark fermentation

Principal Investigator: Dr. Pratima Gupta

Funding Agency: Chhattisgarh Council of Science & Technology (CCOST), Govt. of Chhattisgarh

Status: Completed 

Project 4:

Title of the project: Microbial Fuel Cell Integrated Microbial Electrolytic Cell Reactor and Study of its Structural and Process Parameter for Economics Production of Bio- Hydrogen by Electrohydrogenesis

Principal Investigator: Dr. Pratima Gupta

Funding Agency: Dept. of Biotechnology (DBT), Govt. of India.

Status: Completed 

 

International Conferences Organized/Short Term Training Programs:

1. Organized International Conference on Recent Advances in Biotechnology and Bio-chemistry (ICRBABB), 2020, during 8-9 Jan, 2020.

2. Organized One Week GIAN course online on “Microbial electrochemical Systems as a platformtechnology and its emerging applications”, during 9-13 Jan, 2023. 

 

SIGNIFICANT ACHIEVEMENTS:

Recognized as top 2% scientist of the world in 2nd consecutive years (2024,2025) according to analysis of Stanford  University, USA and report of Elsevier.

 

 

 

SCOPUS ID:

https://www.scopus.com/authid/detail.uri?authorId=7404234670

Google Scholar:
https://scholar.google.com/citations?user=9DA86AUAAAAJ&hl=en&oi=sra