Lata Sheo Bachan  Upadhyay

Department Bio Technology
Designation Professor
Educational Qualification PhD
E-Mail lupadhyay.bt@nitrr.ac.in
Contact Number 09752510082
Areas of Interest

Biochemistry, Enzyme Technology, Nanotechnology, Biosensor/Sensor development for Clinical and Environmental Application

Publications

Journal Publication in SCI/SCOPUS:                                50+

  1. Nikhil Kumar and Lata Sheo Bachan Upadhyay, Enzyme Immobilization over Polystyrene Surface Using Cysteine Functionalized Copper Nanoparticle as a Linker Molecule, Applied Biochemistry and Biotechnology, Volume 191(3), 21 July 2020, Pages 1247-1257.
  2.   V. Sharma, L. S. B. Upadhyay, and D. Vasanth, Extracellular Thermostable Laccase-Like Enzymes from Bacillus licheniformis Strains: Production, Purification and Characterization, Applied Biochemistry and Microbiology, 2020, Vol. 56, No. 4, pp. 420–432. Publisher Pleiades Publishing, DOI: 10.1134/S0003683820040146.
  3. Sonali Rana and Lata Sheo Bachan Upadhyay, Microbial exopolysaccharides: Synthesis pathways, types and their commercial applications, International Journal of Biological Macromolecules, Volume 157, 2020, Pages 577-583. DOI: 10.1016/j.ijbiomac.2020.04.084
  4. Shraddha Chauhan and Lata Sheo Bachan Upadhyay, (2021) The quest for reusability: The facile and stable immobilization of papain on cysteine functionalized iron oxide nanoparticles activated glass surface, Indian journal of biochemistry and biophysics, Vol 58,  pp 141-147. Scopus http://nopr.niscair.res.in/handle/123456789/56486
  5. Anita Tirkey and Lata Sheo Bachan Upadhyay, (2021) Microplastics: An overview on separation, identification and characterization of microplastics, Marine Pollution Bulletin Vol 170 Article 112604, DOI:10.1016/j.marpolbul.2021.112604
  6. Shraddha Chauhan and Lata Sheo Bachan Upadhyay, (2022) A sensitive conductivity sensor for arsenic detection in environmental samples, Microelectronic Engineering, Volume 253,  Article 111674 DOI:10.1016/j.mee.2021.111674 
  7. Mohit Kumar., Lata Sheo Bachan Upadhyay, Ankush Kerketta, D. Vasanth, (2022) Extracellular Synthesis of Silver Nanoparticles Using a Novel Bacterial Strain Kocuria rhizophila BR-1: Process Optimization and Evaluation of Antibacterial Activity, BioNanoScience, Volume 12, Pages 423-438 DOI:10.1007/s12668-022-00968-0
  8. Sonali Rana and Lata Sheo Bachan Upadhyay (2023) Methylene blue assisted electrochemical detection of bacterial biofilm, Indian Journal of Microbiology, 63, 299–306.
  9. Sonali Rana and Lata Sheo Bachan Upadhyay (July, 2023) Utilization of non-pathogenic bacteria to obtain optimum biofilm production for beneficial applications, Brazilian Journal of Microbiology, 54, 1875–1883.
  10. Anita Tirkey and Lata Sheo Bachan Upadhyay, (2024) Microplastics: Discrete sensors to detect microplastics in environment, International journal of Environmental Science and Technology, Volume 21, 2024, 2357-2366 (online Aug, 2023), 21(2):3, DOI: 10.1007/s13762-023-05151-w
  11. Sakshi Sinha & Lata Sheo Bachan Upadhyay, (2024) Biosensing technology for detection and assessment of pathogenic microorganisms, Future Microbiology, Volume 20, 2025, Pages 57-72, 10.1080/17460913.2024.2417621
  12. Udyan Sharma and Lata Sheo Bachan Upadhyay  (2025) Advanced Bio-sensing Technologies for Sickle Cell Disease Diagnosis, Cell Biochemistry and Biophysics, https://doi.org/10.1007/s12013-024-01584-3
  13. Pratistha Bhagat and Lata Sheo Bacah Upadhyay, (2025) A review towards sustainable analyte detection: Biomimetic inspiration in Biosensor Technology, Journal of Biotechnology Volume 398, Pages 51-65, https://doi.org/10.1016/j.jbiotec.2024.11.015

 

Conference publication (National/ International):             25+

 

1. Pratistha Bhagat and Lata Sheo Bachan Upadhyay, Estimation of oil triglyceride in environmental     sample via nanozyme-based hydrolysis, International Conference on Nanomaterials in Biology, 3-6 Feb 2025, University of Rajasthan Jaipur.

2. Pratistha Bhagat and Lata Sheo Bachan Upadhyay, Green synthesis of Copper oxide nanoparticles using Solanum tuberosum extract to mediate photocatalytic degradation of Methylene blue, International Conference on 'Sustainable Development in Chemical and Environmental Engineering, February 22-24, 2024, Thapar Institute of Engineering and Technology (TIET), Patiala.

3. Anita Tirkey and Lata Sheo Bachan upadhyay, Facile synthesis of nickel oxide nanoparticles and its application photocatalytic remediation of crystal violet dye, International Conference on 'Sustainable Development in Chemical and Environmental Engineering, February 22-24, 2024, Thapar Institute of Engineering and Technology (TIET), Patiala.

4. Anita Tirkey and Lata Sheo Bachan Upadhyay, Microbial degradation of LDPE microplastic from microbes found in sediments of dump area National Conference on Food Biotechnology: Trends and Challenges, June, 2021, Lucknow, India.

5. Anita Tirkey and Lata Sheo Bachan Upadhyay, Microbial degradation of LDPE microplastic from microbes found in sediments of dump area World Nano Congress on Advanced Science and Technology, 8th-13th March, 2021, Centre for Nanotechnology Research-VIT Vellore.

6. Lata Sheo Bachan Upadhyay, Reecha Sahu , Shraddha Chauhan , Sonali Rana , Kolli Venkata, Supraja and Amit Kumar, Development of an Aptamer and Nanoparticle based Bioconjugate and its Application in Amphicillin Detection, World Nano Congress on Advanced Science and Technology, 8th-13th March, 2021, Centre for Nanotechnology Research-VIT Vellore.

7. Shraddha Chauhan and Lata Sheo Bachan Upadhyay, The quest for reusability:The facile and stable immobilization of papain on cysteine functionalized iron oxide nanoparticles activated glass surface, International Conference on Recent Advances on Biotechnology and Biochemistry, 8th to 9th January 2020, NIT Raipur, India.

8. Development of an aptamer and nanoparticle based bioconjugate and its application in ampicillin detection,  Lata Sheo Bachan Upadhyay, Reecha Sahu, Shraddha Chauhan, Sonali Rana, Kolli Venkata Supraja, Amit Kumar International Conference on Recent Advances on Biotechnology and Biochemistry, 8th to 9th January 2020, NIT Raipur, India.

9. Shraddha Chauhan and Lata Sheo Bachan Upadhyay, Paper based analytical device: a sustainable and instrument free approach for colorimetric detection of arsenic, Biological Engineering Society Conference and Annual meeting, 26th to 27th October 2018, IIT Bombay, India.

10. Shraddha Chauhan and Lata Sheo Bachan Upadhyay, Biosensor an emerging technology for rapid identification of therapeutic agents, World Biotechnology Congress, 20-22 Feb 2017, JNU New Delhi, India.

 

Book Chapters Published :                                                              

1. Lata Sheo Bachan Upadhyay and Nishant Verma, Chapter Title: Role of Biosensors in Environmental Monitoring, Environmental Microbial Technology, Springer ISBN 978-3-319-19017-4, pg no 77-90.

2. Reecha Sahu and Lata Sheo Bachan Upadhyay, Title: Microbes & Nanotechnology: A potent confluence, Microbial advances in Agriculture and Human Health, Apple Academic Press, Inc., Canada, CRC Press, a Taylor &  Francis group.

3. Lata Sheo Bachan Upadhyay and Aditya Dutt, Chapter Title: Microbial Detoxification of Residual Organophosphate Pesticides in agricultural Practices, Microbial Biotechnology Vol. 1 Application in Agriculture and Environment, Sringer Nature Singapore, ISBN 978-981-10-6846-1, page no 225-242.

4. Nikhil Kumar and Lata Sheo Bachan Upadhyay, Title: Polymeric gels for biosensing applications, Polymeric Gels:Charactterization, Properties and Biomedical Applications, Woodhead Publishing Elsevier, ISBN 978-0-08-102179-8, page no 487-504.

5. Shraddha Chauhan, Reecha Sahu and Lata Sheo Bachan Upadhyay, Chapter Title: Medicinal Plants: A Potent Antimicrobial Source and An Alternative to Combat Antibiotic Resistance, Ethnopharmacology and Biodiversity of Medicinal Plants, pp.239-264, eBook ISBN9780429398193, Imprint: Apple Academic Press (https://doi.org/10.1201/9780429398193)

6. Shraddha Chauhan and Lata Sheo Bachan Upadhyay, Chapter Title: Biosensor: A Boon for Heavy Metals Detection in Natural Water Reservoirs at Higher Altitudes, Microbiological Advancements for Higher Altitude Agro-Ecosystems & Sustainability, Springer,  page no 393-410, DOI: 10.1007/978-981-15-1902-4_19.

7. Lata Sheo Bachan Upadhyay, Sonali Rana and Nikhil Kumar, Chapter Title: Nanomaterials in tissue engineering: Applications and challenges, Advances in Nanotechnology-Based Drug Delivery Systems, Elsevier, Pages 533-554, DOI:10.1016/B978-0-323-88450-1.00018-1  

8. Lata Sheo Bachan Upadhyay and Nikhil Kumar, Chapter Title: Nanocarriers: A boon to the drug delivery systems, Advances in Nanotechnology-Based Drug Delivery Systems, Elsevier, Pages 555-584, DOI:10.1016/B978-0-323-88450-1.00019-3  

9. Shraddha Chauhan, Anita Tirkey and Lata Sheo Bachan Upadhyay, Chapter Title: Nanomaterials in biomedicine: Synthesis and applications, Advances in Nanotechnology-Based Drug Delivery Systems, Elsevier, Pages 585-604, DOI:10.1016/B978-0-323-88450-1.00023-5  

10. Pratistha Bhagat and Lata Sheo Bachan Upadhyay, Recent Advance and development in 3D Printable Biosensor, Soft Material Based Biosensing Medical Applications, Scrivener Publishing/Wiley Group 2025.

 

Patents Granted/ Published

1. Title of Invention: An optical sensor for biofilm detection, Application no 202321058983A, Date of Publication: 19.04.2024, Inventors: Lata Sheo Bachan Upadhyay and Sonali Rana.

2. Title of Invention: An enzyme based optical biosensing device for accurate fluoride estimation   Application no 202321059698 A, Date of Publication: 19.04.2024 Inventors: Lata Sheo Bachan Upadhyay and Nikhil Kumar

3. Continuous closed device for biofilm culturing (Design No 397430-001) Granted on 12.10.2023 Inventors: Lata Sheo Bachan Upadhyay and Sonali Rana 

4. Title of Invention: Compact Biosensor based on Laccase modified Screen Printed Carbon Electrode for Arsenic Determination, Application No. 202321007040, Date of Publication: 20/10/2023, Inventors: Lata Sheo Bachan Upadhyay and Shraddha Chauhan 

5. Title of Invention: A method of fabrication of lipase immobilized glass bead system using l-aspartate functionalized zinc oxide nanoparticles as a bi-linker, Application No. 202111056491 Date of Publication: 09/06/2023, Inventors: Lata Sheo Bachan Upadhyay and Reecha Sahu

Other Info.

 Education (Post-Graduation onwards) and Professional Career

University/Institution

 

Degree

Awarded

Year

Field of Study

Savitribai Phule Pune University, Pune 

B.Sc

1998

Chemistry

Savitribai Phule Pune University, Pune

M.Sc

2000

Biochemistry

Banaras Hindu University, Varanasi

Ph.D

2007

Biochemistry

Position and Employment

Institution Place

Position

From (Date)

To (date)

NIT Raipur

Professor

27.11.2023 

Till Date

NIT Raipur

Associate Professor

11.6.2018

26.11.2023

NIT, Raipur

Assistant Professor

25.07.2008

11.6.2018

Elphinstone College, Mumbai

Lecturer

July 2007

June 2008

Sponsored Research Projects  

Sl No.

Title of Project

Funding Agency

Amount (lac)

 

1

Application of selective plant metabolites to modulate antibiotic efflux pump and inhibition of biofilm developed by antibiotic-resistant Escherichia coli liable for urine infection (Co-PI)

ICMR Ongoing

47.25

 

2

Development of complete functional blood vessel network on multi layered microfluidic platform (Co-PI)

SPARC  Completed

49.19

 

3

Lipase catalyzed bio diesel production from non edible oils by lipolytic bacteria (PI)

SERB-DST (Completed)

19.0

4

Enzymatic Transesterification of NSAID (PI)

CCOST (Completed)

2.0

5

Micro extraction analysis of toxicants in a single drop of environmental and biological samples Co-PI)

CCOST (Completed)

1.84

 

Administrative Responsibilities:

  1. Associate Dean Faculty Welfare
  2. Head, Department of Biotechnology: 2014-2018 and 2021-2023
  3. Head, Department of Biomedical Engineering: 2019-2021
  4. Chairman (Student Club, Cultural Committee): 2012-Till date
  5. Member Institute Ethical Committee: 2014-2023
  6. Member, Sports Purchase Committee: 2019-2020 and 2022-2023
  7. Member Anti ragging committee: 2010-till date

B.Tech Project Supervised 30+

PhD Guidance: 06 Awarded, 01 submitted and 04 ongoing

Dr Nishant Verma, Thesis Title: Development of an Electrochemical Biosensor for Phosphate estimation in Water Samples and Biological Fluids  

Dr Nikhil Kumar, Thesis Title: Development of an Optical Biosensor for Fluoride Determination

Dr Aditya Dutta, Thesis Title: Development of an Immobilized Lipase System for Biodiesel Production from non edible oils

Dr Reecha Sahu, Thesis Title: Studies on Isolation, Partial Characterization, and Production of a Bacterial Lipase and its Immobilization on glass beads for enantio-selective synthesis of 4®-hydroxycyclopent-2-en-1-(s)-acetate.

Dr Shraddha Chauhan, Thesis Title: Development of Biosensing tool for Arsenic Detection

Dr Sonali Rana, Thesis Title:  Fabrication of Sensing Device for Biofilm Detection in Environmental and Biological Systems

Ms Anita Tirkey Thesis Title: Isolation, Characterization and Remediation of Microplastic from Environmental samples and Fabrication of a Sensing Tool for its Detection (Submitted)

Ms Pratistha Bhagat, Thesis Title: Development of a Sensing Platform for Detection of Triglyceride (Ongoing)

Mr Udyan Sharma, Thesis Title: Development of sensing tool for detection of sickle cell disease (Ongoing)

Ms Sakshi Sinha, Thesis Title: Development of Sensing tool(s) for Detection of Antimicrobial- Resistant Microorganism(s) (Ongoing)

Ms Deepanwita Mohanty, Course Work under Progress