Dr. Dijendra Nath Roy

Department Bio Technology
Designation Assistant Professor (Sr. Grade)
Educational Qualification PhD (CSIR-Indian Institute of Chemical Biology)
E-Mail dnr_20@hotmail.com; dnroy.bt@nitrr.ac.in
Contact Number 8974264812
Areas of Interest

Broad Area: Medical Biotechnology

Specialization: Drug Design & Development; Bacterial Biofilm and Antimicrobial Drug Resistance; Medicinal Plants; Antimicrobial Surface; Environmental Toxicology

Publications
Book Published
  1. Dijendra Nath Roy (Editor); Book Title: "TERPENOIDS AGAINST HUMAN DISEASES”; ISBN: 9780815370666; Edition Number: 1st; March 18, 2019; [CRC Press, Taylor and Francis Group, USA].
  2. Dijendra Nath Roy (Editor); Book Title: "A COMPLETE GUIDEBOOK ON BIOFILM STUDY”; ISBN: 9780323884808; Edition Number: 1st; June 22, 2022; [Academic Press, Elsevier, USA]. 
Publications in Peer Reviewed International Journals (SCI/SCOPUS)
  1. S Moulick, DN Roy*; Bioflavonoid baicalein modulates tetracycline resistance by inhibiting efflux pump in Staphylococcus aureus; Microbial Drug Resistance; 30 (9), 363-371 (2024); [Mary Ann Liebert, Inc; Impact Factor: 2.5 (SCI)]
  2. S Datta, V Singh, S Nag*, DN Roy*; Carvacrol, a monoterpenoid, binds quorum sensing proteins (LasI and LasR) and swarming motility protein BswR of Pseudomonas aeruginosa, resulting in loss of pathogenicity: An in silico approach; Canadian Journal of Microbiology; (2024) [Canadian Science Publishing Group; Impact factor: 2.0 (SCI)]
  3. N Moktan, RL Gajbhiye, T Sahithi, DN Roy, R Kundu, A Banerjee*; Antibacterial and antibiofilm activities of extract and bioactive compounds from Bergenia ciliata (Haw.) Sternb. flowers against Streptococcus mutans through cell membrane damage; Journal of Ethnopharmacology; (2024); 119144 [Elsevier Publishing Group; Impact factor: 5.0 (SCI)]
  4. C Mahapatra, S Jadhav, P Kumar, DN Roy, A Kumar*, MK Paul*; Potential activity of nanomaterials to combat SARS-CoV-2 and Mucormycosis‎ coinfection‎; Expert Review of Anti-infective Therapy; (2024); [Taylor and Francis Publishing Group; Impact factor: 4.5 (SCI)]
  5. DN Roy*, A Tandi, A Pal; Moringa oleifera leaf extract functions as a potent inhibitor of snake venom; Journal of Herbs, Spices & Medicinal Plants; (2024), 1-17 [Taylor and Francis Publishing Group; Impact factor: 1.5 (SCOPUS)]
  6. S Datta, V Singh, S Nag, DN Roy*; Marine-derived cytosine arabinoside (Ara-C) inhibits biofilm formation by inhibiting PEL operon proteins (Pel A and Pel B) of Pseudomonas aeruginosa: An in silico approach; Molecular Biotechnology (2024); [Springer Publishing Group; Impact factor: 2.7 (SCI)]
  7. S Kumar, S Datta, V Dey*, DN Roy*; Alteration of stainless-steel surface potential by modifying topography inhibits the development of bacterial biofilm; Journal of Materials Research; 39 (8), 1273-1288 (2024); [Springer Publishing Group; Impact factor: 2.7 (SCI)]
  8. S Kumar, S Datta, V Dey*, DN Roy*; Formation of nanocones and generation of negative potential on stainless steel surfaces by electrochemical etching synergistically reduce Pseudomonas aeruginosa's biofilm; Surface Review and Letters; 2450109 (2024); [World Scientific Publishing Group; Impact factor: 1.5 (SCI)]
  9. S Datta, S Nag, DN Roy*; Biofilm-producing antibiotic-resistant bacteria in Indian patients: a comprehensive review; Current Medical Research and Opinion; 40(3), 403-422 (2024); [Taylor and Francis Publishing Group; Impact factor: 2.3 (SCI)] 
  10. M Majumdar, V Singh, TK Misra, DN Roy*; In silico studies on structural inhibition of SARS-CoV-2 main protease Mpro by major secondary metabolites of Andrographis paniculata and Cinchona officinalis; Biologia, 77(5):1373-1389 (2022); [Springer Publishing Group; Impact factor: 1.7 (SCI)]
  11. S Kumar, DN Roy*, V Dey*; A comprehensive review on techniques to create the anti-microbial surface of biomaterials to intervene in biofouling; Colloid and Interface Science Communications; 43, 100464 (2021); [Elsevier Publishing Group; Impact factor: 5.6 (SCI)]
  12. M Majumdar, A Dubey, R Goswami, TK Misra, DN Roy*; “In vitro and in silico studies on the structural and biochemical insight of anti-biofilm activity of andrograpanin from Andrographis paniculata against Pseudomonas aeruginosa; World Journal of Microbiology and Biotechnology,36,1-18 (2020) [Springer Publishing Group; Impact factor: 4.3 (SCI)]
  13. M Majumdar, SA Khan, NB Nandi, S Roy, AS Panja, DN Roy, TK Misra*; “Green synthesis of iron nanoparticles for investigation of biofilm inhibition property”; Chemistry Select,5,13575-13583 (2020) [Wiley Publishing Group; Impact factor: 2.3 (SCI)]
  14. M Majumdar, SA Khan, SC Biswas, DN Roy, AS Panja, TK Misra*; “In vitro and in silico investigation of anti-biofilm activity of Citrus macroptera fruit extract mediated silver nanoparticles”; Journal of Molecular Liquids,302,112586 (2020) [Elsevier Publishing Group; Impact factor: 6.6 (SCI)]
  15. M Majumdar, TK Misra, DN Roy*; “In vitro anti-biofilm activity of 14-deoxy-11, 12-didehydroandrographolide from Andrographis paniculata against Pseudomonas aeruginosa”; Brazilian Journal of Microbiology,51,15-27 (2020) [Springer Publishing Group; Impact factor: 2.5 (SCI)]
  16. M Majumdar, SC Biswas, R Choudhury, P Upadhyay, A Adhikary, DN Roy, TK Misra*; “Synthesis of Gold Nanoparticles Using Citrus macroptera Fruit Extract: Anti-Biofilm and Anticancer Activity”; Chemistry Select,4,5714-5723 (2019) [Wiley Publishing Group; Impact factor: 2.3 (SCI)]
  17. B Debnath, M Majumdar, M Bhowmik, KL Bhowmik, A Debnath*, DN Roy*; “The effective adsorption of tetracycline onto zirconia nanoparticles synthesized by novel microbial green technology”; Journal of Environmental Management ,261,110235 (2020) [Elsevier Publishing Group; Impact factor: 8.9 (SCI)]
  18. A Pal, R Goswami, DN Roy*; “A critical assessment on biochemical and molecular mechanisms of toxicity developed by emerging nanomaterials on important microbes”; Environmental Nanotechnology, Monitoring & Management,100485 (2021) [Elsevier Publishing Group; Cite Score: 13.0 (SCOPUS)]
  19. S Nag, A Mondal, DN Roy, N Bar, SK Das*; "Sustainable bioremediation of Cd (II) from aqueous solution using natural waste materials: Kinetics, equilibrium, thermodynamics, toxicity studies and GA-ANN hybrid modelling", Environmental Technology & Innovation , 11, 83-104, (2018) [Elsevier Publishing Group, Impact factor:7.7 (SCI)]
  20. DN Roy*#, R Goswami#, A Pal; “The Insect repellents: A silent environmental chemical toxicant to the health”; Environmental Toxicology and Pharmacology, 50,91-102 (2017) [Elsevier Publishing Group; Impact factor: 5.7 (SCI)]#Equal contribution
  21. A Pal, DN Roy*; “Biochemical and Molecular Mechanisms of Liver Damage-Induced by Antidepressant Drugs: an Update Review”, Current Hepatology Report,16, 271–275, (2017) [Springer Publishing Group, (SCOPUS)]
  22. DN Roy*, R Goswami, A Pal; “Nanomaterial and Toxicity: what can proteomics tell us about the NANOTOXICOLOGY?”; Xenobiotica; 47(7): 632–643 (2017) [Taylor and Francis Publishing Group; Impact Factor: 2.0 (SCI)]
  23. R Choudhury, M Majumder, DN Roy, S Basumallick*, TK Misra*; “Phytotoxicity of Ag Nanoparticles Prepared by Biogenic and Chemical Methods”, International Nano Letters, 6(3), 153-159 (2016) [Springer Publishing Group, (SCOPUS)]
  24. DN Roy*, R Goswami; "Drug of abuse and addiction: A slippery slope towards liver injury", Chemico-Biological Interactions, 255, 92-105 (2016) [Elsevier Publishing Group, Impact factor:5.2 (SCI)]
  25. Y Wang, VK Rao, WK Kok, DN Roy, S Sethi, BMT Ling, MBH Lee, R Taneja*; “SUMO modification of Stra13 is required for repression of cyclin D1 expression and cellular growth arrest”, PLoS One, 7(8) e43137, (2012) [Plos Publishing Group, Impact factor:3.0 (SCI)]
  26. DN Roy, G Sen, KD Chowdhury, T Biswas*; “Combination therapy with andrographolide and D-penicillamine enhanced therapeutic advantage over monotherapy with D-penicillamine in attenuating fibrogenic response and cell death in the periportal zone of liver in rats during copper toxicosis”, Toxicology and Applied Pharmacology, 250, 54-68, (2011) [Elsevier Publishing Group,Impact factor:4.5 (SCI)]
  27. DN Roy, S Mandal, G Sen, S Mukhopaddhyay, T Biswas*; "14-deoxyandrographolide desensitizes hepatocytes to TNF-alpha induced apoptosis through calcium dependent TNFR1 release via NO/cGMP pathway"; British Journal of Pharmacology, 160, 1823 – 1843, (2010) [Wiley Publishing Group, Impact factor:9.4 (SCI)]
  28. DN Roy, S Mandal, G Sen, T Biswas*; "Superoxide anion mediated mitochondrial dysfunction leads to hepatocyte apoptosis preferentially in the periportal region during copper toxicity in rats", Chemico-Biological Interactions , 182, 136–147, (2009) [Elsevier Publishing Group, Impact factor: 5.2 (SCI)]
Book Chapters
  1. DN Roy, R Goswami*; Chapter:”IL-9 Signalling Pathway –An Update”; Book Title: Th9 Cells: Methods and Protocols ; ISSN: 1064-3745, Edition Number: 1st; 1585, 21-35 2017 [Springer Publisher].
  2. M Majumdar, S Shivalkar, A Pal, ML Verma, AK Sahoo*, DN Roy*; Chapter:”Nanotechnology For Enhanced Bioactivity of Bioactive Compounds”; Book Title: Biotechnological Production of Bioactive Compounds ; ISBN:9780444643230, Edition Number: 1st; 433-466, 2019 [Elsevier Publisher].
  3. A Pal, R Das, M Kumar, DN Roy*; Chapter:”Application of nanoscience and nanotechnology towards advancement of safety issues of foods”; Book Title: Biotechnological Approaches in Food Adulterants; ISBN:9780367369866, Edition Number: 1st; 282-307, 2020 [CRC Press Publisher].
  4. U Mahapatra, A Pal, AK Manna, DN Roy*; Chapter:”Genome assessment: Functional gene identification involved in heavy metal tolerance and detoxification”; Book Title: Soil Bioremediation: An approach towards sustainable cleaner technology ; ISBN:978-1119547952, Edition Number: 1st; 51-86, 2021 [John Wiley & Sons Publisher].
  5. N Moktan, DN Roy, A Banerjee*; Chapter: "Role of genetically modified organism in biodegradation and detoxification—current challenges and perspectives"; Book Title: Microbiome-assisted Bioremediation; ISBN: 9780443219115, Edition Number: 1st; 221-239, 2024 [Elsevier Publisher].  
*Corresponding author
Other Publications:
  1. DNROY; Microbial Biofilm Causes of Biological Fouling of Materials; Cognition (Querterly Research Newsletter of NIT Raipur), Volume 3; Issue 2, July 2023
Other Info.
Work Experience:
  • Assistant Professor (Grade - I), Department of Biotechnology, NIT Raipur, Chhattisgarh, India (January 2024 to Till Present)
  • Assistant Professor (Grade - II), Department of Biotechnology , NIT Raipur, Chhattisgarh, India (July, 2021 to December 2023)
  • Assistant Professor, Department of Bio Engineering, NIT Agartala, Tripura, India (January, 2013 - June, 2021)
  • Post Doctoral Research Fellow, National University of Singapore (May 2011 - December 2012)

Sponsored Research Projects/Grants from External/Internal Agency:

Internal Agency

1. Grant Scheme: Research Seed Grant 
    Principal Investigator : Dr. Dijendra Nath Roy
    Agency: NIT-Raipur (Govt of India)
    Status: Ongoing

2. Grant Scheme: Start-up Seed Grant for Students 
    Faculty Mentor: Dr. Dijendra Nath Roy
    Agency: Innovation Development Cell of NIT-Raipur (Govt of India)
    Status: Ongoing

External Agency

1. Project Scheme: Investigator Initiated Research Scheme
    Principal Investigator: Dr. Dijendra Nath Roy
    Agency: ICMR (Govt of India)
    Status: Ongoing

2. Project Scheme: Mini Research Project Scheme
    Principal Investigator: Dr. Dijendra Nath Roy
    Agency: CGCOST (Govt of Chhattisgarh)
    Status: Ongoing

3. Project Scheme: DST Fast Track Young Scientist Scheme with Start Up Research Grant
    Principal Investigator: Dr. Dijendra Nath Roy
    Agency: SERB (DST, Govt of India)
    Status: Completed

4. Project Scheme: Grant-in-aid for Research & Development in Engineering & Technology
    Principal Investigator : Dr. Dijendra Nath Roy
    Agency: Institute of Engineers (India)
    Status: Completed

5. Project Scheme: DBT Twinning Project for NE region
    Co-Investigator (I): Dr. Dijendra Nath Roy
    Agency: DBT, Govt of India
    Status: Completed

PhD Students Guidance:

  1. Dr. Moumita Majumdar (As Joint Guide) - Status [Awarded, Currently Postdoctoral Associate at University of Georgia, USA]
  2. Mr. Sanjay Kumar (As Joint Guide) - Status [Submitted, Currently Faculty at Kamla Nehru Institute of Technology, Sultanpur, UP, INDIA]
M.Tech Student's Project Guidance :
  1. Ms. Aparajita Roy [Awarded in 2021, followed by PhD student at IIT-Guwahati)] 
  2. Ms. Banhisikha Debnath [Awareded in 2019, followed by PhD student at IIT-Guwahati)]
  3. Ms. Leichombam Devi Menon [Awareded in 2017, followed by PhD student at IIT-Guwahati)]
  4. Mr. Manna Majumder [Awareded in 2016]
Workshop/Conference/Course Conducted at NIT-Raipur:
  1. Conducted the 5 Days GIAN Course on "Microbial electrochemical Systems as a platform technology and its emerging applications", January 16 - 20, 2023 as one of the Course Coordinators
  2. Organized the 19th Chhattisgarh Young Scientist Congress (CYSC-2024) [26th and 27th Feb, 2024] as one of the Joint Secretaries and as Theme Coordinator of Biology (Zoology, Botany & Chemical Biology) division, Jointly conducted by National Institute of Technology Raipur and Chhattisgarh Council Of Science & Technology, Raipur, Chhattisgarh.

Subjects Taught at NIT-Raipur

Theory:

  1. Unit Operation - Odd Semester
  2. Basic Bioscience - Odd Semester
  3. Microbiology - Odd Semester
  4. Bioinformatics - Odd Semester
  5. Food Biotechnology - Odd Semester 
  6. Immunology - Even Semester
  7. Cell and Molecular Biology - Even Semester
  8. Genetics -  Even Semester
  9. Interactomics - Even Semester

Laboratory:

  1. Unit Operation Lab - Odd Semester
  2. Bioinformatics Lab - Odd Semester
  3. Basic Bio Science Lab - Odd Semester
  4. Heat and Mass Transfer Lab - Odd Semester
  5. Immunotechnology Lab - Even Semester
  6. Cell and Molecular Biology - Even Semester

Award and Honours:

  • Young Scientist Award under DST Fast Track Scheme (December-2015) by DST, Govt of India
  • Recipient of Post-Doctoral Research Fellowship from National University of Singapore for 2 years (April 2011- May 2013) and a recipient of an additional SGD 2000 Bonus for outstanding performance in the year of 2012 (January-December) from NUS, Singapore.
  • PhD Fellowship (JRF + SRF) for Five Years from CSIR, Govt of India, for GATE qualified Engineering Graduate, (August 2005 - July 2010)
  • National Merit Scholarship, 2001
  • Expert Member of State level Expert of Appraisal Committee (SEAC) for State of Tripura for environmental clearance, nominated by Ministry of Environment, Forest and Climate Change, Government of India for 3 years (2014-2017)
  • Peer Reviewer of Several International Publishers (eg., ACS, Elsevier, Taylor & Francis, Springer)

Administrative Responsibility at NIT-Raipur:

  • Departmental Faculty Coordinator of "CDC and Training Placement Cell" of Institute - July 2022 Onwards
  • Member of Anti Ragging Committee - 2022 Onwards
  • Joint Faculty Advisor of Students Batch 2021-22 of Biotechnology Department
  • Member of Departmental Academic Committe of Biotechnology - September 2023 Onwards
  • Convener of Departmental Grievance Committe of Biotechnology - September 2023 Onwards
  • Faculty In-Charge of Time Table (Biotechnology Department) - September 2023 Onwards
  • Member of Departmental Out Reach Activity Committee - Septemeber 2023 Onwards
  • Faculty Co-ordinator of PhD Students for Viksit Bharart@2047 Mission- January 2024 Onwards
  • Faculty Co-ordinator of Industry Institute Collaboration Cell - June 2024 Onwards
  • Assistant Exam Superintendent (5th Semester, Department of Biotechnology, 2024 Nov)

Membership of Society/Organization:

  • Life Member of Association of Microbiologists of India (AMI) [ID:5457-2023]
  • Life Member of Biotech Research Society, India (BRSI) [ID:LM2795]
  • Life Member of Society of Biological Chemists, India (SBCI) [ID:4711]
  • Life Member of Indian Science Congress Association (ISCA) [ID:L19641]
  • Member of Institute of Engineers (IEI, INDIA), Chemical Engg Division [M-151092-9]
  • Member of ORCID [A non-profit organization] (ID:0000-0002-8826-9471)

 

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