Dr. Santhosh  Penta

Department Department of Chemistry
Designation Assistant Professor
Educational Qualification Ph.D (NIT-Warangal), Post-Doctorate (UoH))
E-Mail santhoshpenta07@gmail.com; spenta.che@nitrr.ac.in
Contact Number 8305654728
Areas of Interest
  • Synthetic Organic Chemistry
  • Heterocyclic Chemistry
  • Novel Methodologies
  • Drug Design of Pharmaceutical Importance




1. A facile synthesis of aryl substituted hydrazonopyrazolyl[1,2,4]triazolo[3,4-b][1,3,4][thiadiazol]-coumarin         


    Archi Sharma, Gudala Satish, Santhosh Penta

     Journal of Heterocyclic Chemistry:   2014 (Accepted)

2. An efficient one-pot synthesis of pyrazolyl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazin-6-yl)-2H-pyran-2-one derivatives

    via multicomponent approach and their potential antimicrobial and nematicidal activity.      

    Santhosh Penta and Rajeswar Rao Vedula

     Tetrahedron  Letters-2013, 54, 5663-5666

3. Synthesis of 2,4,6-tri-substituted pyridine derivatives in aqueous medium via Hantzsch multicomponent reaction

    catalyzed by cerium (IV) ammonium nitrate.

    Santhosh Penta and Rajeswar Rao Vedula

     Journal of Heterocyclic Chemistry-2013, Vol.50, 859-862.

4. A new convenient, one pot method for the synthesis of Thiazolyl-pyrazolones from dehydroacetic acid derivative via

    multicomponent approach.

    Santhosh Penta and Rajeswar Rao Vedula 

     Synthetic Communication-2012, Vol.42, 3395-3402

5. Environmentally friendly, one-pot synthesis of substituted thiazoles and thiazolyl-pyrazoles.

    Santhosh Penta and Rajeswar Rao Vedula

     Russian Journal of General Cemistry-2012, 82, 1464-1467

6. A facile one-pot synthesis of 1,3,4-thiadiazine-5-yl-pyran-2-one derivatives via multicomponent reaction

    Santhosh Penta and Rajeswar Rao Vedula 

     Journal of Sulfur Chemistry: 2011, Vol. 32, 327-333

7. One-pot synthesis of tri-substituted pyrazoles via multicomponent approach

    Santhosh Penta, Chunduru, V. S. R and Rajeswar Rao Vedula

     Chemistry of Heterocyclic Compounds:   2011, No.4, 547-551



1. An efficient improved one-pot synthesis of thiazolo[2,3-c][1,2,4]triazol-5-yl)-2H-chromen-2- one derivatives via

    multi-component approach.

    Santhosh Penta and Rajeswar Rao Vedula                                         

     Indian Journal of Chemistry-2014, Vol 53B, 115-119



1. Presented a paper in National Seminar on “New Vistas in Chemistry During 21st Century” 11th-12th September 

    2009, held at Pingle Govt. College for Women, Warangal.

2. Presented a paper in International Conference on “Recent advances in drug discovery” 22nd-24th October, 2010, 

    held at Kakatiya University, Warangal.

3. Presented a paper in National Conference on “Recent Advances in Heterocyclic Chemistry” 4th-5th Nov, 2011, held

    at JNTU Hyderabad.

4. Presented a paper in 3rd International Conference on Heterocyclic Chemistry 10th-13th Dec, 2011, held at

    University of Rajasthan, Jaipur.

5. Participated in Science Academies lecture workshop on Current Trends In Nanoscience And Technology, December 

    23rd-24th, 2011, held at Department of Chemistry, National Institute of Technology,  Warangal.

6. Presented a paper in National Conference on Interface between chemical Sciences and Technologies, 29th-30th

    December 2011, held at Department of Chemistry, National Institute of Technology, Warangal.

7. Accepted a paper in 13th Florida Heterocyclic and Synthetic International Conference on “Synthesis of heterocyclic

    compounds by multi-component reactions” 4th-7th March, 2012, held at, Gainesville, U.S.A.

8. Participated in short term course on “Recent trends in material science-II” Sep-30th –Oct 4th 2013 Organized by

    Department of Physics, National Institute of Technology-Raipur, C.G.

9. Participated in lecture workshop on “Recent Advances in Synthesis and Medicinal Applications of Heterocyclic

    Compounds" (RASMAHC), November 8th-10th, 2013, held at Department of Chemistry, National Institute of

    Technology, Warangal.

10.  Given an oral presentation entitled “ A facile synnthesis of pyridinyl 1,2,4-triazinyl-chromen-2-derivatives via 

       multicomponent approach” for oral presentation in 32nd Annual Conference Indian Council of Chemists 

       28th-30th November 2013, Department of studies in chemistry, Karnatak University, Dharwad.

11.  Given an oral presentation on “an efficient one-pot synthesis of pyran substituted dihydropyrimidine-2(1H)-ones

       and thiones and their anticancer activity:  A Biginelli approach” in International Conference (organized by 

       department of chemistry vikrama Simhapuri University and UNT health science center Fort Worth, Texas, USA)

       conducted in vikrama simhapuri university, Nellore, Andhra Pradesh on 27-29 December 2013. 

12.  Accepted a paper in 6th international conference on Drug Discovery & Therapy on “synthesis of novel 1-(4-(2H-

      chromen-3-yl)thiazol-2-yl)-3,5 dimethyle-2-phenyl-1-H-,2-H-,3,4 bi pyrazole-5-ol derivatives” on feb-10-12,  

         2014, held at Dubai.

13.  Participated a workshop on ACADEMIC ETHICS AND IPR organized by National Institute of Technology and

      Chhattisgarh council of science and technology on 04-05 April, 2014 in National Institute of Technology, Raipur.  

14.  Given an oral presentation on “A facile synthesis of [1,2,4]triazolo[3,4-b][1,3,4]thiadiazinyl-pyran-2-one

      derivatives via ring transformation reaction” in Recent Development in Chemical Science and Technology: Young

      Scientists’ Meet (RDCST -2014) 15-16 March. (NIT, ROURKELA).

15.  Given a lecture on “Modification Strategies for Development of Bioactive Heterocyclic Compounds” in Short term

      Training Programme on Recent Trends in Heterocyclic Compounds and Material Science, organized by Dept of

       Chemistry, NIT-Raipur, 26-30, May 2014.


Other Info.


SPONSORED PROJECTS (Ongoing)                                            

  • Project entitled “Design and synthesis of novel potent heterocyclic compounds and their biological evaluation” for a period of 3 years (2014-2017) by Chhattisgarh Council of Science and Technology (Rs. 4,95,000.00) as Principal Investigator


SHORT TERM TRAINING PROGRAMME ORGANISED                                                   

  •  “Recent Trends in Heterocyclic Compounds and Material Science” from May 26-30, 2014,    Department of Chemistry, NIT-Raipur.

          Coordinators: Dr. Santhosh Penta and Dr. S.P. Mahapatra


 MEMBERSHIP IN SCIENTIFIC SOCIETY                                                                          


  • Since 2013      :     Life time member, Indian Council of Chemists, Agra, India
  • Since 2013      :     Life time member, The Indian Science Congress Association, India
  • Since 2013      :     Life time member, Materials Research Society of India, IISC, India
  • Since 2013      :     Life time member, Indian Chemical Society, Kolkata, India



  • Expertise in multi-step synthesis.
  • Reflective knowledge and good skills in synthesis of heterocyclic molecules.
  • Capable of designing and development of new strategies for biological active compounds.
  • Extensively worked on chromatographic separation and structure analysis.
  • Experiences in parallel synthesis include the design, synthesis, purification and characterization of new chemical entities
  • Capable of carrying independent and collaborative research work.
  • Profound efficiency in handling of hygroscopic, air sensitive reagents and reactions.